Tuesday, June 30, 2009

Rat Paradise - Where Drug Addiction Is No Longer An Issue For Rats Or Humans Who Are Not In Cages

Rat Park - It's not the drug, it's the box [cage] ...
http://suboxforum.com/viewtopic.php?p=1444
 
In the late 1970's, Bruce Alexander conducted the Rat Park experiments in an attempt to better understand the effects of environment on addiction. Instead of keeping his junky (adicted) rats alone in a wire cage with nothing but heroin to do, he built them a rat paradise.

The rats in Rat Park showed some curious behavior: when presented with an unlimited supply of morphine, they chose plain fresh water instead. He even added sugar to the morphine water to make it more appealing, and still the rats just said No.
Quote:
A Skinner box is a cage equipped to condition an animal’s behaviour through reward or punishment. In a typical drug test, a surgically implanted catheter is hooked up to a drug supply that the animal self-administers by pressing a lever. Hundreds of trials showed that lab animals readily became slaves to such drugs as heroin, cocaine, and amphetamines. “They were said to prove that these kinds of dope are irresistible, and that’s it, that’s the end of the addiction story right there,” Alexander says. After one particularly fruitless seminar in 1976, he decided to run his own tests.

The problem with the Skinner box experiments, Alexander and his co-researchers suspected, was the box itself. To test that hypothesis, Alexander built an Eden for rats. Rat Park was a plywood enclosure the size of 200 standard cages. There were cedar shavings, boxes, tin cans for hiding and nesting, poles for climbing, and plenty of food. Most important, because rats live in colonies, Rat Park housed sixteen to twenty animals of both sexes.

Rats in Rat Park and control animals in standard laboratory cages had access to two water bottles, one filled with plain water and the other with morphine-laced water. The denizens of Rat Park overwhelmingly preferred plain water to morphine (the test produced statistical confidence levels of over 99.9 percent). Even when Alexander tried to seduce his rats by sweetening the morphine, the ones in Rat Park drank far less than the ones in cages. Only when he added naloxone, which eliminates morphine’s narcotic effects, did the rats in Rat Park start drinking from the water-sugar-morphine bottle. They wanted the sweet water, but not if it made them high.
The addicted rats in Rat Park even kicked their habits voluntarily when given the option to do so:
Quote:
In a variation he calls “Kicking the Habit,” Alexander gave rats in both environments nothing but morphine-laced water for fifty-seven days, until they were physically dependent on the drug. But as soon as they had a choice between plain water and morphine, the animals in Rat Park switched to plain water more often than the caged rats did, voluntarily putting themselves through the discomfort of withdrawal to do so.

Maybe this offers an explanation as to why some people can use addictive drugs without becoming addictive. It might also offer some ideas as to why addiction treatment so often fails. Maybe we're focused on the wrong things. Maybe we need to fix the issues that seem to so often foster addiction [Both physical and mental cages.]: poverty, loneliness, lack of community, lack of spirituality.

Well worth reading: A more in depth chapter from the book - Opening Skinner's Box by Lauren Slater is here.

More articles on Rat Paradise here:
http://neuroanthropology.net/2008/02/08/the-rat-park/
http://the-mouse-trap.blogspot.com/2008/02/rat-park-addiction-and-environmental.html
http://homelessnation.org/en/node/6949


You can read more about the Rat Park experiments here.

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Sunday, June 21, 2009

Children Taking Ritalin & Other ADHD Meds Has 5 Times Risk Of Sudden Cardiac Death

stimulants used to treat children for so-called ADHD can cause sudden cardiac arrest and death in kids.

drugs includes amphetamines like Adderall and Dexedrine and methylphenidate products such as Ritalin, Concerta, and Focalin.

Children and youth age 7 to 19 taking prescribed Ritalin for ADHD were four to five times more likely to die of sudden unexplained cardiac arrest than other children who were not taking Ritalin.

the study was skewed to hide just how many children die of sudden death when taking Ritalin.

Unconscionable, the study researchers were trying not to prove that stimulants cause sudden death in children.

There is also evidence from studies of stimulant addicts and case reports that stimulant drugs can cause heart disease, including inflammation and scarring. When drugs like Ritalin and Adderall are prescribed in routine pediatric doses, they commonly cause hypertension, which can lead to an enlarged heart. Yet children with even slightly enlarged hearts were excluded from the study. So the researchers ended up excluding any children with enlarged hearts caused by the stimulant treatment itself.

The same is true in regard to anorexia. Stimulants commonly cause anorexia. The researchers therefore excluded cases of stimulant-induced death in anorexic patients when the anorexia itself could have been caused by the stimulant.


the answer to this problem is simple.
Don't give stimulants to children.

There are far better non-drug ways to deal with so-called ADHD.

Very often these children improve dramatically when parents develop a more consistent, rational and loving plan for discipline.

Sometimes the problem completely disappears when the child is assigned a better teacher.

the child may be especially full of life and need more opportunity to run, to play, and to be creative.

these children ... don't need toxic drugs that can lead to drug addiction, cause psychosis and depression, stunt growth, impair brain function, and even cause sudden cardiac arrest. 

Our children  ... need us to protect them from misguided health professionals while we make every effort to meet their real needs in our families and schools.
+++


Children taking ADHD medication may be at risk of sudden cardiac death, study finds

Thursday, June 18th 2009, 4:00 AM

A study that links ADHD drugs to an increased risk of sudden cardiac death in children may be driving parents crazy.

If your child has ADHD, a new federally funded study that links ADHD drugs like Ritalin to an increased risk of sudden cardiac death may be making you crazy.

But mental health experts say the research is not conclusive enough for parents to necessarily take their children and teenagers off their medication.

The FDA is saying that the study has its limitations and should not necessarily change the way the stimulant drugs are used, according to WebMD.

The study, funded by the National Institute of Mental Health and the FDA, identified 564 children and teenagers who had died suddenly for unexplained reasons, and who had no structural heart defects.

Researchers also looked at 564 young people who had died as passengers in car accidents, many of whose deaths were later attributed to undiagnosed cardiac problems.

The researchers concluded that the odds of using a stimulant like Ritalin were six to seven times higher among the children who had died suddenly of unexplained causes than among those who died in auto accidents.

The study, which will appear in The American Journal of Psychiatry, does not prove that ADHD drugs cause cardiac deaths but they highlight the importance of screening kids and teens for heart problems before putting them on a stimulant medication, says Charlotte Armstrong, a NIMH spokesperson.

"One of the concerns is that there need to be improvements in screening for cardiac abnormalities in young people before putting them on medications like Ritalin," she says.

She also stressed the need for more studies.

"The bigger the numbers they can look at, the better," Armstrong says.

Dr. Ramon Solhkhah, director of the Child and Family Institute of St. Luke’s Roosevelt Hospital, says that while medication is the "gold standard of treatment for moderate to severe ADHD," some kids may benefit from non-drug therapies.

"There are definitely some behavioral and lifestyle changes that could be beneficial," he says. "These include cognitive behavioral therapy, certain organizational skills, more individual attention in the classroom and life coaches who can get kids organized."

Chiropractor Gerard Clum notes that many young people with ADHD can benefit from chiropractic techniques.

"A number of case reports have been published with chiropractic care and there has been a positive resolution in the severity of symptoms," he says.

And Dr. Robert Melillo, author of "Disconnected Kids," recommends not just behavioral modification, but careful attention to diet and nutrition.

"ADHD medications can help with symptoms," he says. "But there are a lot of alternatives out there that address the underlying problem."
===



Dr. Peter Breggin

Stimulants for ADHD Shown to Cause Sudden Death in Children
Dr. Peter Breggin

Posted: June 17, 2009 03:04 PM

A new study, published Monday in the American Journal of Psychiatry, confirms what I've been warning about for years in my scientific books and articles. The stimulants used to treat children for so-called ADHD can cause sudden cardiac arrest and death in kids. The study was published by the journal online in advance of regular publication in the near future. On Monday, I had the opportunity to comment on the study on Good Morning America. Here is more detail.

The stimulant group of drugs includes amphetamines like Adderall and Dexedrine and methylphenidate products such as Ritalin, Concerta, and Focalin. The study focused on Ritalin because at the time it was more commonly used than the amphetamines, although amphetamines are probably even more toxic to the heart.

The results of the study were as dramatic as they are tragic. Children and youth age 7 to 19 taking prescribed Ritalin for ADHD were four to five times more likely to die of sudden unexplained cardiac arrest than other children who were not taking Ritalin.

Despite these ominous results, the study was skewed to hide just how many children die of sudden death when taking Ritalin. The study relied heavily on identifying cases through toxicology reports at autopsy. But autopsy studies for the detection of these controlled substances are geared to detect more massive doses from addiction and overdose. They are not sensitive enough to detect many cases of routine prescription use. As a result, many stimulant-caused deaths were probably missed.

Also, the study excluded a large number of sudden deaths if the children had even the slightest evidence of pre-existing heart disease. They excluded these children even when the coroner thought that heart disease played no role in the death. For example, if a child was taking stimulants and had minimal heart disease, such as a slightly enlarged heart, the researchers didn't include the case as a possible death due to the stimulant. They also did not count children who were severely obese, anorexic, or asthmatic. But all of these children, especially ones with undetected heart disease, are much more highly at risk for of stimulant-induced sudden death. They even excluded children whose parents had some forms of heart disease.

It's as if they did not want to confirm the obvious--that an examination of children with heart disease and related disorders would swell the numbers of those killed by Ritalin. In fact, the current FDA approved label specifically mentions the risk of cardiac sudden death when Ritalin is given to children with heart conditions.

Unconscionable, the study researchers were trying not to prove that stimulants cause sudden death in children. They made the findings despite their own attempts to avoid it. I was not surprised to find that some of the researchers for this study are among the biggest advocates of psychiatric medications for children.

Sudden cardiac death in children is rare, probably occurring--as the study notes--in a slightly little less than 1 in 100,000 children. But we need to take a few other facts into account. First, the rate is going to be much higher in children taking stimulant drugs. Not just the four or five times higher found in this study, but many more times higher when vulnerable children are included such as those with undetected heart disease, severe obesity, asthma, or anorexia. Second, stimulant drugs are one of the few causes of cardiac death in otherwise normal children, making it impossible to detect the risk before it happens.

There is also evidence from studies of stimulant addicts and case reports that stimulant drugs can cause heart disease, including inflammation and scarring. When drugs like Ritalin and Adderall are prescribed in routine pediatric doses, they commonly cause hypertension, which can lead to an enlarged heart. Yet children with even slightly enlarged hearts were excluded from the study. So the researchers ended up excluding any children with enlarged hearts caused by the stimulant treatment itself.

The same is true in regard to anorexia. Stimulants commonly cause anorexia. The researchers therefore excluded cases of stimulant-induced death in anorexic patients when the anorexia itself could have been caused by the stimulant.

Meanwhile the psychiatric establishment--represented by American Psychiatric Association, NIMH and drug companies--has been quick to dismiss the importance of the study. Instead, they should be emphasizing that the study detected the risk even though the highest risk patients were excluded, including some who were displaying toxic stimulant effects such as heart disease and anorexia.

Meanwhile, it's hard to imagine a greater tragedy for the surviving family than the unexpected death of a child from taking a medication prescribed by a doctor. I've been involved as a medical expert or consultant for families in several tragic cases of stimulant-induced cardiac death. I've also been an expert in cases of suicide in children caused by stimulants. These tragic deaths are always heartbreaking. Years afterward, the emotional wounds remain as raw as ever for their parents and brothers and sisters. The family's trust for doctors and the healthcare system can be forever shattered.

Yet the answer to this problem is simple. Don't give stimulants to children. There are far better non-drug ways to deal with so-called ADHD. ADHD is defined as involving hyperactivity, inattention, and impulsivity. These are not diseases--they are disciplinary and educational problems. Very often these children improve dramatically when parents develop a more consistent, rational and loving plan for discipline. Sometimes the problem completely disappears when the child is assigned a better teacher.

At times the child diagnosed with ADHD is simply a little delayed in learning self-discipline or finding the motivation to study. Often something is distressing the youngster, such as peer ridicule and abuse. Or the child may be especially full of life and need more opportunity to run, to play, and to be creative.

Whatever these children need, they don't need toxic drugs that can lead to drug addiction, cause psychosis and depression, stunt growth, impair brain function, and even cause sudden cardiac arrest. I describe and document all of these adverse stimulant effects, and many more, in my medical book, Brain-Disabling Treatments in Psychiatry: Drugs, Electroshock, and the Psychopharmaceutical Complex, Second Edition (2008).

Our children don't need drugs--they need us to protect them from misguided health professionals while we make every effort to meet their real needs in our families and schools. It's time for all of us to retake responsibility for our children.

Dr. Breggin's latest book is Medication Madness: The Role of Psychiatric Drugs in Cases of Violence, Suicide and Crime (St. Martin's, 2008). It is now in paperback.

Dr. Breggin's website is www.breggin.com.



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